SETD2 Antikörper

Produktnummer ABIN7384153

Dieser Anti-SETD2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SETD2 in IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SETD2 Antikörper (ABIN7384153)

Target: SETD2 (SET Domain Containing 2 (SETD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-SETD2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SETD2 (NP_054878.5).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SETD2

Target: SETD2 (SET Domain Containing 2 (SETD2))

Andere Bezeichnung: SETD2

Hintergrund: SETD2,HBP231,HIF-1,HIP-1,HSPC069,HYPB,KMT3A,LLS,SET2,p231HBP,Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Gen-ID: 29072

UniProt: Q9BYW2

Pathways: Tube Formation